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While generally safe, some individuals may experience gastrointestinal discomfort, allergic reactions, or skin irritation

The effects of phytoestrogens on breast cancer may be also caused by their ability to inhibit local estrogen synthesis, induce epigenetic changes, and suppression of ER signaling pathways [68, 69]

Hou et al., 2014) (Figure 3)

Most studied accessions exceed FAO/WHO (1991) essential amino acid requirements for children aged 25 years (Akin Idowu et al., 2013), although some reports note tryptophan or valine may be limiting in certain samples (Sidorova et al., 2023)